| Characteristic | Details |
|---|---|
| Active Ingredients | Sildenafil Citrate 100mg, Fluoxetine 40mg |
| Form | Oral Tablets |
| Intended Use | Erectile Dysfunction and Premature Ejaculation |
| Dosage | As prescribed by healthcare provider |
| Manufacturing | Fortune Healthcare |
| Link | Learn More |
Chemical Structure
The chemical structure of Malegra FXT Plus comprises two main components. Sildenafil Citrate, a phosphodiesterase type 5 (PDE5) inhibitor, serves as the primary agent for addressing erectile dysfunction. Its molecular formula is C22H30N6O4S. The structure consists of a piperazine ring linked to a pyrazolo-pyrimidine core. The second component, Fluoxetine, is an SSRI with the formula C17H18F3NO. Its molecular makeup includes a trifluoromethyl group bonded to a phenyl ring. Together, these compounds synergize to enhance male sexual performance.
Mechanism of Action
Malegra FXT Plus exerts its effects through a dual mechanism. Sildenafil Citrate, the first element, inhibits PDE5. This results in increased cyclic guanosine monophosphate (cGMP) within the corpus cavernosum. The outcome is smooth muscle relaxation, leading to augmented blood flow to the penis. Fluoxetine, the second element, augments serotonin levels in the synaptic cleft. It delays ejaculation by enhancing serotoninergic neurotransmission. This dual action manages both erectile dysfunction and premature ejaculation efficiently.
Malegra FXT Plus Contraindications
Malegra FXT Plus presents certain contraindications. Individuals with hypersensitivity to Sildenafil or Fluoxetine should avoid use. Severe cardiovascular disorders also contraindicate use due to potential cardiac stress. Co-administration with nitrates is dangerous due to severe hypotension risk. Additionally, those with a history of serotonin syndrome should not use this medication.
Pregnancy and Breastfeeding
The usage of Malegra FXT Plus is not advised during pregnancy and breastfeeding. Although the medication targets male sexual health, inadvertent exposure can occur. Sildenafil and Fluoxetine may cross the placental barrier. Potential harm to the fetus has not been ruled out. Additionally, traces could pass into breast milk, affecting the infant. Consultation with a healthcare provider is imperative before potential exposure.
Side Effects
Like all medications, Malegra FXT Plus can induce side effects. Common issues include headaches, dizziness, and flushing. Gastrointestinal discomfort may also occur. Serious reactions include priapism and severe hypotension. Monitoring for serotonin syndrome signs is crucial. This includes agitation, confusion, or hallucinations. Immediate medical intervention is necessary if severe side effects manifest.
Malegra FXT Plus Over The Counter
Malegra FXT Plus is not available over the counter. It requires a prescription due to the potent active ingredients. The combination of Sildenafil and Fluoxetine warrants medical supervision. Proper dosage and administration guidelines must be followed. An assessment of cardiovascular health and mental well-being is essential. Safe use of this medication depends on professional medical guidance.
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